Last Updated: Fri, 06 Sep 2013 09:31
Daniel Sturridge's leg injury means he is aleady an early doubt for Liverpool's Premier League visit to Swansea on September 16.
Sturridge has returned to Merseyside after being ruled out of England's encounter with Moldova at Wembley on Friday.
The 24-year-old had a slight thigh injury going into Sunday's win over Manchester United and then suffered a further setback in the game to rule him out of the Three Lions action.
Sturridge will now have further treatment from Liverpool's medical staff before it is decided whether he should link up with Hodgson's squad once more before they leave for Kiev for Tuesday's next World Cup qualifier against Ukraine.
It is a long shot though. In fact, Hodgson wonders whether the former Chelsea man will be available when Liverpool put their 100% start to the season on the line at the Liberty Stadium a week on Monday.
"We have to be honest here," said Hodgson. "Sturridge is doing ever so well to try and make himself available (for Moldova).
"He was devastated to turn up injured. He wanted to be with us and to have the treatment so he could play.
"But the fact is when they did the scan at the beginning of the week, it was going to be touch and go for Tuesday, and possibly even Saturday week.
"He wants to be a part of it. He's young and can recover quickly. We hope there's some good news on Sunday morning and he can come with us and take part. But I'm not enormously optimistic. I'm not confident. We can't put him out there unless he is fit."
Losing Sturridge for any period of time, who missed most of pre-season with an ankle injury, would be a major blow to Reds boss Brendan Rodgers, as the striker has fired all the club's three league goals so far that have all sealed 1-0 wins.
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